Yohimbe Extract, the Raw Material for the Efficient Treatment of Sexual Dysfunction

Yohimbine extract, yohimbine as the symbolic ingredient, is derived from dried bark of African natural plant Corynante Yohimbe. Corynante Yohimbe is an evergreen tree, which is native to Cameroon, Gabon and Congo of southwestern Nigeria. The bark can be used for medicinal purposes. And Africans have processed this plant into herbal Viagra.

Specification: yohimbine 8%, 10% (dark red brown powder); yohimbine HCL 98% (white powder)

Yohimbine HCL is a form of acidification based on 98% yohimbine for better preservation. As it is difficult for alkaloids to exist stably in the case of high purity, so yohimbine HCL 98% will benefit the product storage and transportation and increase its solubility in water, thus it will be better utilized. Currently, the majority of finished Yohimbine extract is not produced in China but in India and the extracting raw materials are from in Africa.

Conventional process:
Stripping the barks, slicing and drying them, smashing the raw materials, putting into pot, adding 12 times amount of 60% ethanol, reflux extraction for 3 times with temperature controlled between 65 ℃ and 85 ℃, the extraction time of 3 hours, 2 hours, 1 hour respectively, filtering the filtrate, merging the filtrate for the 3 times, decompressing and condensing into the extractum with the relative density of 1.10-1.20 (at room temperature), spray drying, destroying into 80 mesh powder, entering warehouse after packing and testing, then the yohimbine extract will be obtained. For high content of yohimbine HCL 98%, extraction, chromatography, crystallization and other processes are further required to achieve the purity of 98%.

Physical properties:
Melting point: 288 ℃-290 ℃, optical rotation: +100 °, easily soluble in chloroform, soluble in methanol, ethanol, slightly soluble in water.
Shelf life: Two years
Preservation: Place it in a cool, dry, dark environment to avoid high temperature.

Mechanism of action:
Yohimbine HCL will increase penile blood flow and raise the formation of nitrous oxide through expanding the penile artery for engorgement and erection, as well as sexual function enhancement. It is known as the pure plant product for the treatment of erectile dysfunction.
In addition, Yohimbine HCL can generate psychological excitement, improving sexual desire. Taking a small amount, perineum could be swelling, stimulating the spinal cord erection center and enhancing sexual function.

The clinical efficacy:
Clinical single dose of yohimbine extract is used for the treatment of various types of male impotence and sexual dysfunction, realizing easier, harder erection in longer duration. This natural plant extract can replace many therapeutic incompetent prescription drugs and equipment with little side effects.
Yohimbine extract can expand the vascular smooth muscle, reduce the sympathetic nervous tension, and increased penile cavernous sinus blood flow through the expansion of the penile artery. Some older people found that the blood is hard to reach the penis. And good blood flow is an inevitable condition for maintaining erections, and yohimbine extract is easier to achieve it.
Erecting the penis, exciting the central sympathetic nervous, improving the quality of life, and maintaining men in a good state.
In addition, yohimbine extract is also suitable for mental, neurological, vascular and diabetic impotence, to relieve sexual dysfunction caused by stress, tension and fatigue, and to increase the body energy supply.

Precautions:
After taking yohimbine products, you may feel temporary mild dizziness, dry mouth, palpitations, abdominal discomfort and other symptoms, which will generally disappear. Please don’t worry.
Do not take it when you suffer from these diseases: anxiety, chest pain, depression, diabetes, heart disease, high blood pressure, kidney disease, liver disease,  post-traumatic stress disorder (PTSD), prostate problem, and schizophrenia.
Do not take it with these drugs: antidepressants and tricyclic antidepressants (heart problem risk), clonidine (hypertension risk) Guanabenze (reduced effectiveness of yohimbine products), hypertensive drug therapy (blood pressure raise risk), stimulants (heart problem risk).

In addition, do not take with these foods and supplements:
these foods and supplements are also contraindicated: any herbal supplements containing caffeine (increased blood pressure risk)，any supplements containing ephedra (increased blood pressure risk), foods that contain tyramine (aged cheese, fermented meats, red wines, etc.), foods that narrow blood vessels (chocolate, coffee, cola, overripe fava beans and tea).
Take it cautiously, then you will experience the unprecedented effect. Of course, if necessary, please consult a doctor if you can take it or not.

Application:
At present, Yohimbine extract is mainly used for male sexual dysfunction or enhance sexual desire. Since it is derived from herbal extracts, not affecting the health of human body with strong effect, it is the best raw materials of health care products, including health wine, medicine nad injection etc.

Xi'an Pincredit Bio-tech Co.,Ltd has achieved a long-term strategic cooperation with international Yohimbine bark purchase and extracting enterprises, importing the third-party certified Yohimbine extract to meet the global needs with reliable quality and stable supply. Welcome to have your advice and procurement.