Magnolia officinalis extract is derived from magnolia officinalis bark. It is the yellowish-brown to white powder with fragrant smelling and slightly bitter in taste. Chinese Pharmacopoeia pointed out that magnolia officinalis has the property of eliminating dampness and dissolving phlegm, descending qi and eliminating fullness. It is used for the treatment of dampness injury, abdominal swelling and diarrhea, indigestion and stagnation of vital energy circulation, ventosity and constipation, phlegm and retained fluid and dyspnea with cough.
The main active ingredients of magnolia officinalis extract belong to lignans phenolic compounds such as Honokiol, Magnolol, Tetrahhydromagnolol, Isomagnolol, and so on. In addition, it also contains more than 30 volatile components and a variety of alkaloid compounds. General specification: Magnolol ≥2% -98%, and Honokiol 98% 99%, Total magnolol ≥ 2% -98%
In recent years, with the development of modern medicine, people found that magnolol and honokiol have many pharmacological effects, including anti-inflammatory, anti-bacterial, anti-oxidation, anti-tumor, and inhibition of morphine withdrawal reaction etc.
Production Process:
Main efficiency of magnolia officinalis extract
1.Antibacterial
The antimicrobial active ingredient of magnolia officinalis extract is magnolol and honokiol. The minimum inhibitory concentration (MIC) of the two is 6.3 μg / ml for streptococcus mutans. The antibacterial activity ( for streptococcus mutans) was stronger than berberine.
2.Anti-oxidation
Magnolol and honokiol have the effect of scavenging free radicals and can remove hydroxyl radicals and hydrogen peroxide. At the same time, it will protect mitochondrial respiratory chain enzyme activity through confronting peroxidation pressure induced by NADPH, antagonize the red blood cell hemolysis, inhibit lipid peroxidation. The study proved the antioxidant activity of magnolia officinalis extract is 1000 times stronger than that of α-tocopherol.
3.For digestive tract
Magnolol and honokiol have an inhibiting effect on gastric ulcer. Magnolol can prevent gastric dysfunction.
4.Platelets inhibition
Magnolol and honokiol can inhibit the circulation of thromboxane B2 and intracellular Ca with the effect of inhibiting platelets.
Magnolol and honokiol have a lasting central muscle relaxation activity. Magnolol can significantly inhibit glutamic acid, the spinal cord excitatory transporter, inhibiting central nervous function.
5.Anti-virus, immunity improvement, anti-inflammatory, anti-liver damage.
Magnolol is an effective component of anti-hepatitis virus.
Magnolol can improve the function of T cell subsets in the body.
Magnolol has the effect of reducing capillary permeability, inhibiting leukoplania and inhibiting fibrous tissue hyperplasia.
Magnolol has the effect of lowering serum ALT and blood ammonia nitrogen for the treatment of acute experimental liver injury. It can significantly prevent the formation of immune liver fibrosis and cirrhosis and improve viral and immune liver disease pathological damage.
Clinical application of magnolia officinalis extract:
Treatment of acute and chronic gastroenteritis, stomach pain caused by dysentery, nausea, abdominal pain, diarrhea.
Treatment of constipation, abdominal pain, flatulence, nausea, and vomiting caused by incomplete intestinal obstruction.
Treatment of globus hysteriocus, stomach discomfort, fullness in stomach.
Treatment of muscle ankylosis.
Treatment of chronic hepatitis.
The dosage of magnolia officinalis extract differs in accordance with the different specifications. According to national regulations and literature, daily trial dose recommended by most experts is as follows:
Magnolia officinalis extract application:
With the accelerated process of modernization of traditional Chinese medicine, the extraction of magnolol and honokiol monomer gets more and more attention. Currently in China, there are more than 200 types of Chinese patent medicine using magnolia officinalis as formula and they are widely used in clinical. The demands of magnolia officinalis extract is increasing. Moreover, it is also used in daily use chemicals.
Xi'an Pincredit Bio-tech Co.,Ltd offers high-yield Magnolia extract with adequate inventory and reliable quality. Welcome your visit.
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