2017年5月17日星期三

Angelica Root Extract- Ligustilide 1%-Blood Enrichment and Activation


Angelica root extract is ethanol extract of dry root of umbellifer angelica sinensis. The active ingredients contain ligustilide, n-butylidene phthalide, ferulic acid, nicotinic acid, sucrose and various amino acids as well as sesquiterpenoids. It is mainly used for enriching the blood and activating blood, and boosting immunit. In 2015 China Pharmacopoeia, angelica root extract has the effects of enriching the blood and activating blood, regulating menstruation and relieving pain, relaxing bowel. The general specification: Ligustilide 1%.

Process:
Angelica root extract is derived from the dry root of angelica sinensis. Harvesting in late autumn, removing the fibrous roots and sediment, after the water is slightly evaporated, tying into wisps, putting on shed, smoke seasoning with smoke and fire. Putting raw materials into pot and add 12 times amount of solvent, reflux extraction for 3 times at low temperature between 50 and 65 , extraction time for 3 hours, 2 hours, 1 hour respectively, filtering the extract, merging the filter liquor of the 3 times,concentrating under reduced pressure to extractum with the relative density of 1.10-1.20 (room temperature), spray drying, destroying into 80 mesh powder, entering warehouse after packing and testing, then the angelica root extract will be obtained.

Ligustilide, one of the main ingredient of angelica root extract, is light yellow grease with fragrance. The studies have shown that ligustilide is helpful of antispasmodic, asthma, and sedative effect. It can improve microcirculation, loosing smooth muscle, inhibiting germ, and improve the body's immune regulation function.

Pharmacological effects of angelica root extract:

1.For the treatment of bronchitis and gynecological diseases.
It is help for chronic bronchitis, relaxing tracheal smooth muscle and confronting bronchial asthma caused by histamine - acetylcholine.
It can be used for the treatment of irregular menstruation, dysmenorrhea, uterine hypoplasia and other gynecological diseases with good clinical results. It is generally used with other prescriptions to achieve better effect.
It is applied to pale or chlorosis, fatigue, lips pale, dizzy, palpitations, and insomnia embolism caused by heart and liver blood deficiency, especially for the treatment of blood deficiency after childbirth.
It is applied to the heart and blood deficiency caused by , especially for postpartum blood deficiency regulation
Inhibit inhibiting womb, make rhythmic contraction in flaccid state, and confront uterine contractions.
2. Anti-thrombotic effect.
Ligustilide can reduce blood viscosity, significantly reducing the weight of thrombosis and decreasing thrombosis growth rate.
3.Nervous system inhibition
Ligustilide has effects of sedative, hypnotic, analgesic, anesthesia and so on.
 4.For relieving eye fatigue and skin wrinkle resistance
 5.For inhibiting tumour

Application:
Angelica root extract is used as the raw material of pharmaceuticals, health products.
Relying on rich Chinese herbal medicine resources in Qinling Mountains, Xi'an Pincredit Bio-tech Co.,Ltd has been dedicated to the development and production of natural plant extracts, the products are used to support functional health food production enterprises with reliable quality and stable supply.

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